A good Cagliari fought to the finish against Roma, but at the Olimpico the final blow fell to the Giallorossi: the match finished 4-2, despite Maldini's equaliser in the 81st minute.

Cagliari made four changes compared to Bologna, lining up with a 3-4-2-1 formation . Mancini had his first chance in the 4th minute, with a foray into the box on the right, but Caprile blocked his shot with his foot. A corner from the left, on the other side, deflected to the near post, and Pisilli touched it with his arm: referee Feliciani allowed play to continue, but VAR called for a clear penalty. Nzola sent Gollini the wrong way from the spot, making it 0-1 and the Angolan's first goal for the Rossoblu . It was the 10th minute, and shortly after, Rodríguez attempted a run with the ball at his feet but was stopped on the edge of the box.

Cagliari's lead lasted just five minutes, and after 15 minutes, Roma equalized with a move from the left by Molina and a cross for winger Lulli, who headed the ball past Obert to make it 1-1. Immediately afterward, Lulli broke through from the right, playing the ball in for Castro, whose deflection missed the target. But by the 21st minute, Roma were already ahead, with Lulli this time managing to provide the assist and crossing for Pisilli to deflect the ball into the net .

Cagliari falters, finding themselves behind and at the mercy of the Giallorossi's pressure. On the half-hour mark, Molina tries, but his deflection leads to a corner. Then the Rossoblu recovers and comes close to equalizing in the 34th minute: Adopo shoots, Gollini makes a great save, and Nzola taps in the rebound with his right foot to send the ball out for a corner . The Angolan strikes again in the 43rd minute, but his left-footed shot goes wide. Halftime is called after a minute.

Roma resumed with Wesley replacing Molina, while Cagliari remained with the same eleven. After Castro's deflected right-footed shot was easily scored by Caprile (48'), . The Giallorossi goalkeeper was instead called upon in the 54th minute, blocking a fine right-footed shot from Deiola from the edge of the area that went over the crossbar.